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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39078 | CXCR7 antagonist-1 | CXCR7 antagonist-1 | CXCR |
CXCR7 antagonist-1 is a specific antagonist of the binding of the SDF-1 chemokine or I-TAC to the chemokine receptor CXCR7. CXCR7 antagonist-1 prevents tumor cell proliferation and tumor formation and can be used in stud... | |||
T62325 | CXCR7 antagonist-1 hydrochloride | ||
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (also known as CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. hydrochloride can be u... | |||
T1776 | Plerixafor | JM3100,AMD 3100,AMD-3329 | Virus Protease , HIV Protease , CXCR |
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. | |||
T75801 | TC14012 TFA | ||
TC14012 TFA, a serum-stable derivative of T140, is a selective peptidomimetic CXCR4 antagonist with an IC50 value of 19.3 nM. It also acts as a potent CXCR7 agonist, exhibiting an EC50 of 350 nM for recruiting β-arrestin... | |||
TP2141L | Balixafortide | POL6326 | CXCR |
Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM and it is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects[1]... | |||
T75999 | Balixafortide TFA | ||
Balixafortide TFA (POL6326 TFA) is a potent, selective CXCR4 antagonist that exhibits excellent tolerance levels and demonstrates an IC50 of less than 10 nM. It displays over 1000-fold selectivity for CXCR4 over a large ... |